4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1,2,3,5-tetrahydro-1-[2-(1-methylethoxy)ethyl]-2-thioxo- - Names and Identifiers
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1,2,3,5-tetrahydro-1-[2-(1-methylethoxy)ethyl]-2-thioxo- - Physico-chemical Properties
Molecular Formula | C11H15N3O2S
|
Molar Mass | 253.32 |
Density | 1.34±0.1 g/cm3(Predicted) |
Solubility | DMSO : 150 mg/mL (592.14 mM; Need ultrasonic) |
pKa | 8.25±0.20(Predicted) |
Storage Condition | -20°C |
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1,2,3,5-tetrahydro-1-[2-(1-methylethoxy)ethyl]-2-thioxo- - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 3.948 ml | 19.738 ml | 39.476 ml |
5 mM | 0.79 ml | 3.948 ml | 7.895 ml |
10 mM | 0.395 ml | 1.974 ml | 3.948 ml |
5 mM | 0.079 ml | 0.395 ml | 0.79 ml |
Last Update:2024-01-02 23:10:35
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1,2,3,5-tetrahydro-1-[2-(1-methylethoxy)ethyl]-2-thioxo- - Introduction
AZD 3241; VERDIPERSTAT is a chemical substance with a chemical name of C10H8N2S. The following is a description of the nature, use, formulation and safety information of AZD 3241; VERDIPERSTAT:
Nature:
-Appearance: AZD 3241; VERDIPERSTAT is a white or off-white crystalline solid.
-Solubility: Good solubility in polar solvents such as water, alcohols and ethers.
-Melting Point: AZD 3241; The melting point of verdiffstat is 80-84 ℃.
Use:
- AZD 3241; VERDIPERSTAT has antioxidant activity and can be used as an antioxidant.
-It also has a certain anti-inflammatory effect and can be used in the treatment of some inflammation-related diseases.
Preparation Method:
The method of preparing AZD 3241; VERDIPERSTAT can be carried out by the following steps:
1. First, benzoic acid and thiocarbamide react under alkaline conditions to generate 2-thio -6-methyl pyrrolidine -4-one.
2. Subsequently, it was oxidized with boiling water and sodium sulfoxinates to obtain 2-thio-6-methylpyrrolidin-4-on-1-oxide.
3. Finally, AZD 3241 was obtained by acid-catalyzed reaction with Phenylboronic acid; VERDIPERSTAT product.
Safety Information:
- AZD 3241; VERDIPERSTAT has low toxicity, but it still needs to be handled in accordance with laboratory safety instructions.
-When using, you need to avoid direct contact with skin and eyes, and avoid inhaling its dust.
-Avoid contact with strong oxidants and strong acids to avoid unnecessary chemical reactions.
Please note that this is a general introduction, specific use, preparation and safety information should be based on the specific situation and laboratory requirements for the exact understanding and operation.
Last Update:2024-04-10 22:29:15